Martin O'Toole
Assoc Professor
Education
- B.A. in Chemistry, University of Louisville, 1998
- M.S. in Chemistry, University of Louisville, 2007
- Ph.D. in Chemistry, University of Louisville, 2008
Publications
Journal Articles
- Sherwood, L., C., Aqil, F., Vadhanam, M., V., Jeyabalan, J., Munagala, R., Hoetker, D., Srivastava, S., Singh, I., P., Cambron, S., D. & O'Toole, M., G. (2017). Development of a goat model for evaluation of withaferin A: Cervical implants for the treatment of cervical intraepithelial neoplasia. Experimental and molecular pathology, 103(3), 320-329
- Tamiya, S., Chauhan, R., Balgemann, R., Noma, H., McDonald, K., Kaplan, H., J. & O'Toole, M., G. (2017). Production and characterization of a sustained release system of dasatinib to prevent proliferative vitreoretinopathy. Investigative Ophthalmology & Visual Science, 58(8), 4759-4759
- Bates, P., Reyes-Reyes, E., Malik, M., T., Murphy, E., O'Toole, M., G. & Trent, J. (2016). G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms.. Biochimica et Biophysica Acta (BBA) – General Subjects
- Brann, T., Patel, D., Chauhan, R., James, K., Bates, P., Malik, M., Keynton, R. & O'Toole, M., G. (2016). Gold Nanoplates as Cancer-Targeted Photothermal Actuators for Drug Delivery and Triggered Release. Journal of Nanomaterials
- O'Toole, M., G., Soucy, P., A., Chauhan, R., Raju, M., V., Patel, D., N., Nunn, B., M., Keynton, M., A., Ehringer, W., D., Nantz, M., H., Keynton, R., S. & Gobin, A., S. (2016). Release-Modulated Antioxidant Activity of a Composite Curcumin-Chitosan Polymer. Biomacromolecules, 17(4), 1253-1260
- James, K., O'Toole, M., G., Patel, D., Zhang, G., Gobin, A., M. & Keynton, R., S. (2015). A High-Yield, Controllable Process for Producing Tunable Near Infrared-absorbing Gold Nanoplates. RSC Advances, 5, 12498-12505
- Malik, T., M., O'Toole, M., G., Cassen, L., K., Thomas, S., D., Bardi, G., T., Reyes-Reyes, E., M., NG, C., K., Kang, K., A. & Bates, P., J. (2015). AS1411-conjugated gold nanoparticles and their potential for breast cancer therapy. Nanomedicine: Nanotechnology, Biology, and Medicine, 6(26), 22270-81
- Patel, D., James, K., O'Toole, M., G., Zhang, G., Keynton, R., S. & Gobin, A., M. (2015). A High Yield, One-Pot Dialysis-Based Process for Self-Assembly of Near Infrared Absorbing Gold Nanoparticles. Journal of Colloid and Interface Science, 441, 10-16
- Soucy, P., S., O'Toole, M., G., Brigitte, F., Keynton, M., Jain, I., Ehringer, W., Keynton, R., S. & Gobin, A., S. (2015). Gamma-Irradiation Protection from Low Doses of Curcumin. International Journal of Nanomedicine
- Lucas, T., M., James, K., T., Beharic, J., Moiseeva, E., V., Keynton, R., S., O'Toole, M., G. & Harnett, C., K. (2014). Wavelength Specific Excitation of Gold Nanoparticle Thin-Films. Applied Physics Letters
- Lucas, T., M., James, K., T., Beharic, J., Moiseeva, E., V., Keynton, R., S., O'Toole, M., G. & Harnett, C., K. (2014). Wavelength specific excitation of gold nanoparticle thin films. Applied Physics Letters, 104, 011909
- Sun, X., Zhang, G., Keynton, R., S., O'Toole, M., G., Patel, D. & Gobin, A., M. (2013). Enhanced Drug Delivery via Hyperthermal Membrane Disruption Using Targeted Gold Nanoparticles with PEGylated Protein-G as a Cofactor. Nanomedicine: Nanotechnology, Biology and Medicine, 9(8), 1214-1222
- Kang, K., A., Wang, J., O'Toole, M., G., Nantz, M., Moore, J., D., Laulhe, S. & Achilefu, S. (2012). Sensitivity enhancement of NIR fluorescence contrast agent utilizing gold nanoparticles. Advances in Experimental Medicine and Biology, 737, 285-91
- O'Toole, M., G., Henderson, R., M., Soucy, P., A., Fasciotto, B., H., Hoblitzell, P., J., Keynton, R., S., Ehringer, W. & Gobin, A., S. (2012). Curcumin encapsulation in submicrometer spray-dried chitosan/tween 20 particles. Biomacromolecules, 13(8), 2309-2314
- Allen, N., C., Chauhan, R., Bates, P., J. & O'Toole, M., G. (2022). Optimization of Tumor Targeting Gold Nanoparticles for Glioblastoma Applications. Nanomaterials (Basel, Switzerland), 12(21)
- Beharic, J., James, K., T., Keynton, R., S., O'Toole, M. & Harnett, C., K. (2021). Impact of microfabrication processing temperatures on the resonant wavelength of gold nanoplates. Materials Letters, 284, 128967
- Chauhan, R., Balgemann, R., Greb, C., Nunn, B., M., Ueda, S., Noma, H., McDonald, K., Kaplan, H., J., Tamiya, S. & O'Toole, M., G. (2019). Production of dasatinib encapsulated spray-dried poly (lactic-co-glycolic acid) particles. Journal of Drug Delivery Science and Technology, 53, 101204
- Chauhan, R., Balgemann, R., Greb, C., Nunn, B., M., Ueda, S., Noma, H., McDonald, K., Kaplan, H., J., Tamiya, S. & O'Toole, M., G. (2019). Production of dasatinib encapsulated spray-dried poly (lactic-co-glycolic acid) particles. Journal of Drug Delivery Science and Technology, 53, 101204
- Chauhan, R., El-Baz, N., Keynton, R., S., James, K., T., Malik, D., A., Zhu, M., El-Baz, A., Ng, C., K., Bates, P., J., Malik, M., T. & O'Toole, M., G. (2019). Targeted Gold Nanoparticle⁻Oligonucleotide Contrast Agents in Combination with a New Local Voxel-Wise MRI Analysis Algorithm for In Vitro Imaging of Triple-Negative Breast Cancer. Nanomaterials (Basel, Switzerland), 9(5)
- Chauhan, R., El-Baz, N., Keynton, R., S., James, K., T., Malik, D., A., Zhu, M., El-Baz, A., Ng, C., K., Bates, P., J., Malik, M., T. & others, . (2019). Targeted Gold Nanoparticle--Oligonucleotide Contrast Agents in Combination with a New Local Voxel-Wise MRI Analysis Algorithm for In Vitro Imaging of Triple-Negative Breast Cancer. Nanomaterials, 9(5), 709
- Chauhan, R., El-Baz, N., Keynton, R., S., James, K., T., Malik, D., A., Zhu, M., El-Baz, A., Ng, C., K., Bates, P., J., Malik, M., T. & others, . (2019). Targeted gold nanoparticle--oligonucleotide contrast agents in combination with a new local voxel-wise MRI analysis algorithm for in vitro imaging of triple-negative breast cancer. Nanomaterials, 9(5), 709
- Chauhan, R., Kinney, K., Akalkotkar, A., Nunn, B., M., Keynton, R., S., Soucy, P., A. & O'Toole, M., G. (2020). Radiation-induced curcumin release from curcumin--chitosan polymer films. RSC advances, 10(27), 16110--16117
- Chauhan, R., Kinney, K., Akalkotkar, A., Nunn, B., M., Keynton, R., S., Soucy, P., A. & O'Toole, M., G. (2020). Radiation-induced curcumin release from curcumin-chitosan polymer films. RSC advances, 10(27), 16110-16117
- Chowdhury, E., Grapperhaus, C., A. & O’Toole, M., G. (2020). Facet-selective asymmetric functionalization of anisotropic gold nanoprisms for Janus particle synthesis. Journal of Nanoparticle Research, 22, 1--12
- Chowdhury, E., Rahaman, M., S., Sathitsuksanoh, N., Grapperhaus, C., A. & O'Toole, M., G. (2021). DNA-induced assembly of gold nanoprisms and polystyrene beads into 3D plasmonic SERS substrates. Nanotechnology, 32(2), 025506
- Chowdhury, E., Rahaman, M., S., Sathitsuksanoh, N., Grapperhaus, C., A. & O'Toole, M., G. (2021). DNA-mediated hierarchical organization of gold nanoprisms into 3D aggregates and their application in surface-enhanced Raman scattering. Physical chemistry chemical physics : PCCP, 23(44), 25256-25263
- Chowdhury, E., Rahaman, M., S., Sathitsuksanoh, N., Grapperhaus, C., A. & O’Toole, M., G. (2020). DNA-induced assembly of gold nanoprisms and polystyrene beads into 3D plasmonic SERS substrates. Nanotechnology, 32(2), 025506
- Chowdhury, E., Rahaman, M., S., Sathitsuksanoh, N., Grapperhaus, C., A. & O’Toole, M., G. (2021). DNA-mediated hierarchical organization of gold nanoprisms into 3D aggregates and their application in surface-enhanced Raman scattering. Physical Chemistry Chemical Physics, 23(44), 25256--25263
- El-Baz, N., Nunn, B., M., Bates, P., J. & O'Toole, M., G. (2022). The Impact of PEGylation on Cellular Uptake and In Vivo Biodistribution of Gold Nanoparticle MRI Contrast Agents. Bioengineering (Basel, Switzerland), 9(12)
- Ghithan, J., H., Moreno, M., Keynton, R., S., O'Toole, M., G. & Mendes, S., B. (2021). Adsorption Properties and Electron-transfer Rates of a Redox Probe at Different Interfaces of an Immunoassay Assembled on an Electro-active Photonic Platform. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 37(10), 1391-1399
- Qatamin, A., H., Ghithan, J., H., Moreno, M., Nunn, B., M., Jones, K., B., Zamborini, F., P., Keynton, R., S., O'Toole, M., G. & Mendes, S., B. (2019). Detection of influenza virus by electrochemical surface plasmon resonance under potential modulation. Applied optics, 58(11), 2839-2844
- Qatamin, A., H., Ghithan, J., H., Moreno, M., Nunn, B., M., Jones, K., B., Zamborini, F., P., Keynton, R., S., O’toole, M., G. & Mendes, S., B. (2019). Detection of influenza virus by electrochemical surface plasmon resonance under potential modulation. Applied Optics, 58(11), 2839--2844
- Qatamin, A., H., Ghithan, J., H., Moreno, M., Nunn, B., M., Jones, K., B., Zamborini, F., P., Keynton, R., S., O’toole, M., G. & Mendes, S., B. (2019). Detection of influenza virus by electrochemical surface plasmon resonance under potential modulation. Applied optics, 58(11), 2839--2844
- Rahaman, M., S., Phung, T., K., Hossain, M., A., Chowdhury, E., Tulaphol, S., Lalvani, S., B., O’Toole, M., Willing, G., A., Jasinski, J., B., Crocker, M. & others, . (2020). Hydrophobic functionalization of HY zeolites for efficient conversion of glycerol to solketal. Applied Catalysis A: General, 592, 117369
- Tamiya, S., Ueda, S., McDonald, K., Nunn, B., Kaplan, H., J. & O'Toole, M. (2019). Prevention of post-traumatic proliferative vitreoretinopathy using sustained release system of dasatinib. Investigative Ophthalmology & Visual Science, 60(9), 5814--5814
- Tamiya, S., Ueda, S., McDonald, K., Nunn, B., Kaplan, H., J. & O'Toole, M. (2019). Prevention of post-traumatic proliferative vitreoretinopathy using sustained release system of dasatinib. Investigative Ophthalmology & Visual Science, 60(9), 5814--5814
- Ueda, S., Nunn, B., M., Chauhan, R., McDonald, K., Kaplan, H., J., O'Toole, M., G. & Tamiya, S. (2021). Sustained dasatinib treatment prevents early fibrotic changes following ocular trauma. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 259(5), 1103-1111
- Ueda, S., Nunn, B., M., Chauhan, R., McDonald, K., Kaplan, H., J., O’Toole, M., G. & Tamiya, S. (2021). Sustained dasatinib treatment prevents early fibrotic changes following ocular trauma. Graefe's Archive for Clinical and Experimental Ophthalmology, 1--9
- Ueda, S., Nunn, B., M., Chauhan, R., McDonald, K., Kaplan, H., J., O’Toole, M., G. & Tamiya, S. (2021). Sustained dasatinib treatment prevents early fibrotic changes following ocular trauma. Graefe's Archive for Clinical and Experimental Ophthalmology, 259, 1103--1111
More about Martin O'Toole
- Faculty Favorite, 2016, UofL
- Get Healthy Now Member of the Month, 2016, UofL
2023
Spring
- BE 453 - INTRO MOLECULAR BIOENGRG
- BE 359 - CELL & MOLEC BIOL FOR BE
- BE 359 - CELL & MOLEC BIOL FOR BE
2022
Summer
- BE 553 - NANOSCALE BIOENGINEERING
- BE 553 - NANOSCALE BIOENGINEERING
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
- BE 453 - INTRO MOLECULAR BIOENGRG
- BE 491 - ECON, ETHICS & FDA REGS
- BE 553 - NANOSCALE BIOENGINEERING
- BE 553 - NANOSCALE BIOENGINEERING
- BE 553 - NANOSCALE BIOENGINEERING
2021
Spring
- BE 553 - NANOSCALE BIOENGINEERING
Summer
- BE 553 - NANOSCALE BIOENGINEERING
Fall
- BE 553 - NANOSCALE BIOENGINEERING
- BE 453 - INTRO MOLECULAR BIOENGRG
- BE 491 - ECON, ETHICS & FDA REGS
- BE 553 - NANOSCALE BIOENGINEERING
2020
Spring
- BE 553 - NANOSCALE BIOENGINEERING
- BE 359 - CELL & MOLEC BIOL FOR BE
Summer
- BE 553 - NANOSCALE BIOENGINEERING
- BE 359 - CELL & MOLEC BIOL FOR BE
Fall
- BE 553 - NANOSCALE BIOENGINEERING
- BE 359 - CELL & MOLEC BIOL FOR BE
- BE 453 - INTRO MOLECULAR BIOENGRG
- BE 491 - ECON, ETHICS & FDA REGS
2019
Summer
- BE 553 - NANOSCALE BIOENGINEERING
- BE 605 - TISS & MOLEC BIO TECH LAB
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
- BE 491 - ECON, ETHICS & FDA REGS
2018
Fall
- BE 553 - NANOSCALE BIOENGINEERING
- BE 453 - INTRO MOLECULAR BIOENGRG
Summer
- BE 354 - ANATOMY AND PHYSIOLOGY
- BE 605 - TISS & MOLEC BIO TECH LAB
Spring
- BE 354 - ANATOMY AND PHYSIOLOGY
2017
Summer
- BE 450 - BIOMATLS & BIOCOMPATIBILITY
- BE 605 - TISS & MOLEC BIO TECH LAB
- BE 693 - INDEPENDENT STUDY IN BE
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
2016
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
Summer
- BE 605 - TISS & MOLEC BIO TECH LAB
- BE 693 - INDEPENDENT STUDY IN BE
2015
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
Summer
- BE 605 - TISS & MOLEC BIO TECH LAB
Spring
- BE 693 - INDEPENDENT STUDY IN BE
2014
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
Summer
- BE 605 - TISS & MOLEC BIO TECH LAB
Spring
- BE 359 - CELL & MOLEC BIOL FOR BE
2013
Fall
- BE 453 - INTRO MOLECULAR BIOENGRG
Summer
- BE 605 - TISS & MOLEC BIO TECH LAB